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ea0070oc9.6 | Reproductive and Developmental Endocrinology | ECE2020

Testosterone replacement therapy of opioid induced male hypogonadism improved body composition but not pain perception A double-blinded, randomized and placebo-controlled trial

Glintborg Dorte , Bjarke Vægter Henrik , Lehmann Christensen Louise , Bendix Emma , Graven-Nielsen Thomas , Andersen Per Grunwald , Andersen Marianne

Background: Hypogonadism is prevalent during opioid treatment, but the effect of testosterone replacement treatment (TRT) on body composition, pain perception, and adrenal function is unclear.Purpose: To measure changes in body composition, pain perception, quality of life and adrenal function after TRT or placebo in opioid treated men with chronic non-malignant pain.Methods: Double-blinded, placebo-controlled study in 41 men (&#62...

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Testosterone replacement therapy of opioid induced male hypogonadism improved body composition but not pain perception A double-blinded, randomized and placebo-controlled trial

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